The Clinico-Epidemiological Profile of Patients with Gonorrhoea and Challenges in the Management of Neisseria gonorrhoeae Infection in an STI clinic, Ternopil, Ukraine (2013-2018)
| Autor: | Viorika Akimova, Lyudmyla Mazur, Iryna Savchenko, Ihor Kohut, Iryna Boiko, Inna Krynytska |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Gonorrhea Sexually Transmitted Diseases medicine.disease_cause Azithromycin Young Adult 03 medical and health sciences 0302 clinical medicine Internal medicine Clarithromycin Epidemiology Prevalence medicine Humans 030212 general & internal medicine sexually transmitted infections Aged Retrospective Studies Aged 80 and over 0303 health sciences gonorrhea 030306 microbiology Transmission (medicine) business.industry Medical record General Medicine Middle Aged medicine.disease Neisseria gonorrhoeae Female Original Article epidemiology Syphilis Ukraine business management medicine.drug |
| Zdroj: | Journal of Medicine and Life |
| ISSN: | 1844-3117 1844-122X 2013-2018 |
| DOI: | 10.25122/jml-2019-0170 |
| Popis: | Gonorrhea is the second most common sexually transmitted infection spreading worldwide and a serious public health problem. How�ever, further data are required to improve the management of gonorrhea. Our aim was to review the features of gonococcal infection and characterize the challenges of its management. A retrospective descriptive study of the medical records of 136 adult patients with gonorrhea that visited Ternopil Regional Sexually Transmitted Infections Clinic (Ukraine) in 2013-2018 was performed. The male-to-female ratio was 6.6:1. Homosexually-acquired gonorrhoea was 3.7%. Also, most patients acquired gonorrhea in Ukraine (98.4%). The mean infectious period lasted 2-16 days, including the incubation period of 1-9 days and the period from the onset of symptoms to the first visit of the clinic of 1-7 days. The probability of N. gonorrhoeae transmission within the frame of the epidemiologic sexual chain was 1:2.4. Concurrent T. vaginalis (39.7%) and C. trachomatis (2.2%) were detected. HIV and syphilis screening rates were 1.6% and 0.7%, respectively. The examining rate of sexual partners was 11%, testing extragenital specimens - 0.7%, screening coverage for HIV - 46.3%, compliance with follow-up visits - 41.9%. Part of patients (16.2%) received monotherapy with clarithromycin, doxycycline, benzylpenicillin, azithromycin, or ofloxacin. The management of N. gonorrhoeae infections was compromised by a low rate of examining sexual partners, females and testing extragenital specimens, screening for HIV, compliance to follow-up visits, access to nucleic acid amplification tests, and receiving questionable or even obsolete antimicrobial treatment. Therefore, more accurate and comprehensive management of gonorrhea is urgently needed in Ukraine. |
| Databáze: | OpenAIRE |
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