EFFECT OF ACUTE INTRAVENOUS ACE-INHIBITION ON THE INTRARENAL DOPPLER FLOW CHARACTERISTICS IN HYPERTENSIVE PATIENTS WITH AND WITHOUT UNILATERAL RENAL ARTERY STENOSIS

Autor:	G. R. Hetzel, Ulrich Mödder, Bernd Grabensee, Mathias Cohnen, Adina Voiculescu, J. Malms, Markus Hollenbeck, Reinhart Willers
Rok vydání:	2000
Předmět:	Male medicine.medical_specialty Duplex ultrasonography Physiology Angiotensin-Converting Enzyme Inhibitors Blood Pressure Renal Artery Obstruction Essential hypertension Renal artery stenosis Renal Circulation Renovascular hypertension Duplex scanning Internal medicine Internal Medicine medicine Humans Ultrasonography Doppler Duplex Vascular disease business.industry General Medicine Middle Aged medicine.disease Surgery Stenosis Hypertension Renovascular medicine.anatomical_structure Enalaprilat Injections Intravenous Vascular resistance Cardiology Female Vascular Resistance business
Zdroj:	Clinical and Experimental Hypertension. 22:571-581
ISSN:	1525-6006 1064-1963
DOI:	10.1081/ceh-100100092
Popis:	Assessment of intrarenal doppler signals is of particular importance in screening for renal artery stenosis. We studied the effect of acute ACE-inhibition (1,25 mg enalaprilate i.v.) on intrarenal resistive indices in 10 hypertensive patients with unilateral renal artery stenosis versus 10 patients with essential hypertension. Any changes limited to poststenotic vessels could possibly improve the diagnostic value of duplex sonography. After ACE-inhibition a significant fall of the intrarenal Resistive Index occurred in both patient groups. In cases of unilateral renal artery stenosis we saw a tendency to an increased side difference of the Resistive Index due to a greater fall on the poststenotic side. Therefore a clear advantage of duplex scanning after acute ACE-inhibition due to a limited effect of enalaprilate on poststenotic vessels was not found. The results suggest that the vascular resistance and not only the degree of renal artery stenosis is of significance for the characteristics of the doppler signal.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc533ce4deb39d4511f26efed5148ebd https://doi.org/10.1081/ceh-100100092 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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