Association between the duration of diabetes and gram-negative bacterial infection in diabetic foot infections: a case-control study

Autor: Siyong, Chen, Xianpei, Tan, Xia, Li, Tongfeng, Zhao
Rok vydání: 2022
Předmět:
Zdroj: Endocrine Journal. 69:1061-1065
ISSN: 1348-4540
0918-8959
DOI: 10.1507/endocrj.ej21-0690
Popis: This retrospective case-control study was designed to explore the association between the duration of diabetes and gram-negative bacterial infection in diabetic foot infections (DFIs). All DFI patients hospitalized in the Department of Endocrinology in the Sixth Affiliated Hospital of Sun Yat-sen University between 2013 and 2019 with positive microbial culture results were included. Cases were defined as DFI patients whose microbial cultures grew gram-negative bacteria (including polymicrobial flora). Controls were defined as DFI patients whose positive microbial cultures did not grow gram-negative bacteria. Clinical data were extracted from the hospital information system. Stabilized inverse probability weighting was used to balance between-group differences at baseline. Confounders were selected using a directed acyclic graph. Missing data were imputed with the multiple imputation of chained equations method. Odds ratios (ORs) with 95% confidence intervals (CIs) and P
Databáze: OpenAIRE