Malformação venosa associada a hiperelasticidade cutânea e atrofia do tecido subcutâneo
| Autor: | Salvador José de Toledo Arruda Amato, Ricardo Virginio dos Santos, Ana Julia de Deus Silva, Alexandre Campos Moraes Amato |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Pathology medicine.medical_specialty lcsh:Diseases of the circulatory (Cardiovascular) system medicine.medical_treatment lcsh:Surgery Connective tissue dermatopatias vasculares 030204 cardiovascular system & hematology Thigh Flaccidity doenças vasculares Lesion 03 medical and health sciences 0302 clinical medicine malformações vasculares Biopsy medicine Embolization biology medicine.diagnostic_test business.industry anormalidades da pele Anatomy lcsh:RD1-811 doenças do colágeno medicine.disease 030104 developmental biology medicine.anatomical_structure lcsh:RC666-701 biology.protein medicine.symptom Cardiology and Cardiovascular Medicine business Venous malformation Elastin |
| Zdroj: | Jornal Vascular Brasileiro, Iss 0 (2016) |
| ISSN: | 1677-7301 |
| Popis: | In syndromes that involve reduced quantities of elastin, the rigidity of vein walls may be increased, causing venous malformations, even in people who have mosaicism for these syndromes. There are no previous descriptions in the literature of collagen diseases presenting in specific, delimited areas. The patient described here presented with a lesion restricted to a well-defined area of the anteromedial thigh, in which elasticity was increased and vessels were tortuous, in the area of the lesion only, and with no other signs of collagen syndromes. A biopsy was conducted and the findings included changes to the normal arrangement of the elastic fibers and proliferation of blood vessels. The venous malformation was treated satisfactorily by embolization. Collagen diseases can cause cutaneous hyperextensibility, provoking flaccidity and a propensity to traumatisms. Connective tissue diseases restricted to well-delimited areas are rare, since this group of diseases usually has systemic involvement. Vascular malformations can be seen in many different collagen diseases, but with generalized rather than localized presentation. One possible explanation for the case described here is genetic mosaicism. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|