Rapid aetiological diagnosis of pneumonia based on routine laboratory features
| Autor: | Hans Holmberg, Ingegerd Jönsson, Lennart Bodin, Aud Krook |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Microbiology (medical)
Adult medicine.medical_specialty Adolescent Blood Sedimentation medicine.disease_cause Haemophilus influenzae Leukocyte Count White blood cell Internal medicine Pneumonia Mycoplasma medicine Humans Aged Aged 80 and over General Immunology and Microbiology medicine.diagnostic_test L-Lactate Dehydrogenase business.industry Respiratory disease Age Factors Routine laboratory Discriminant Analysis Alanine Transaminase General Medicine Pneumonia Middle Aged Pneumonia Pneumococcal medicine.disease Infectious Diseases medicine.anatomical_structure C-Reactive Protein Erythrocyte sedimentation rate Immunology Etiology business Chlamydial infection |
| Zdroj: | Scandinavian journal of infectious diseases. 22(5) |
| ISSN: | 0036-5548 |
| Popis: | The values of some basic laboratory features on admission to hospital were recorded and compared in 418 adult patients with community-acquired pneumonia, namely erythrocyte sedimentation rate, C-reactive protein, white blood cell (WBC) count, serum lactate dehydrogenase (S-LD), serum alanine-aminotransferase, and serum sodium. Discriminant analysis was performed to obtain an aetiological diagnosis. WBC value of greater than 15 x 10(9)/l strongly indicated a bacterial and, especially a pneumococcal aetiology, whereas increased S-LD could imply a mycoplasmal infection. For patients less than 50 years of age the equation C2 = -1.788 + 0.204 x WBC-0.0909 X S-LD was constructed, in which C2 greater than 0 indicated a pneumococcal aetiology. This function correctly classified 31/33 (93.9%) patients with a mycoplasmal and 20/31 (64.5%) patients with a pneumococcal infection. Patients with viral, Haemophilus influenzae or chlamydial infection could not be discriminated from each other. The age of the patient, WBC and possibly S-LD on admission are easily accessible parameters and these results could therefore be of value in daily clinical practice in hospitals. |
| Databáze: | OpenAIRE |
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