Mixed squamous and large-cell carcinoma of the lung: A case study and literature review
| Autor: | Iris Karachaliou, Stamatis Katsenos, Stavros Archondakis |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Male
squamous cell carcinoma Pathology medicine.medical_specialty Lung Neoplasms medicine.medical_treatment lcsh:RC254-282 Carcinoma Humans Medicine Radiology Nuclear Medicine and imaging Lung Pathological Chemotherapy Brain Neoplasms business.industry Large cell Transbronchial lung biopsy Histology General Medicine Middle Aged Prognosis medicine.disease lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens Neoadjuvant Therapy Carcinoma Neuroendocrine Survival Rate Mixed Tumor Malignant medicine.anatomical_structure Oncology large-cell neuroendocrine carcinoma immunohistochemistry Carcinoma Squamous Cell Combined lung tumor Carcinoma Large Cell Immunohistochemistry business |
| Zdroj: | Journal of Cancer Research and Therapeutics, Vol 8, Iss 3, Pp 445-447 (2012) |
| ISSN: | 1998-4138 0973-1482 |
| Popis: | Lung tumors with combined histological pattern are seldom seen exhibiting a more aggressive clinicopathological picture than tumors with a single histology. Herein, we present a 58-year-old male with mixed squamous and large-cell lung carcinoma. The patient was initially diagnosed through fluoroscopy-guided transbronchial lung biopsy with large-cell lung carcinoma of the left upper lobe. He received neo-adjuvant chemotherapy and then underwent left upper lobectomy. Postoperative pathological diagnosis was combined squamous and large-cell neuroendocrine carcinoma. Two months after surgery, restaging revealed brain metastatic deposits. Local radiotherapy was promptly applied with relatively good response and the patient is under observation eight months after diagnosis. A brief review of the current literature is also included with special emphasis on the clinicopathologic aspects and prognosis of lung tumors with mixed histology. |
| Databáze: | OpenAIRE |
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