Modic Changes in the Lumbar Spine are Common Aging-related Degenerative Findings that Parallel With Disk Degeneration
| Autor: | Xiangjin Lin, Michele C. Battié, Yue Wang, Lunhao Chen, Xiaojian Hu, Jingfeng Zhang |
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| Rok vydání: | 2018 |
| Předmět: |
Male
Aging Population Degeneration (medical) Intervertebral Disc Degeneration Body Mass Index 03 medical and health sciences 0302 clinical medicine Lumbar medicine Medicine and Health Sciences Humans Orthopedics and Sports Medicine 030212 general & internal medicine education education.field_of_study Lumbar Vertebrae medicine.diagnostic_test business.industry Reproducibility of Results Modic changes Magnetic resonance imaging Odds ratio Anatomy Middle Aged Magnetic Resonance Imaging humanities Surgery Lumbar spine Female Neurology (clinical) business Body mass index 030217 neurology & neurosurgery |
| Zdroj: | Bone and Joint Institute |
| ISSN: | 2380-0194 |
| Popis: | STUDY DESIGN This is a cross-sectional study. OBJECTIVE To determine the prevalence and distribution patterns of Modic changes (MCs) in the lumbar spine and their associations with disk degeneration in mainland Chinese using a sample of general population. SUMMARY OF BACKGROUND DATA Previous studies reported that the prevalence of MCs in Hong Kong Chinese was much lower than in other populations. Moreover, their associations with disk degeneration need further study. MATERIALS AND METHODS The study sample consisted of 442 subjects (53.6±14.9 y; range, 20-88 y) randomly selected from a typical Chinese community. Lumbar spines were imaged using a 3.0 T magnetic resonance scanner. Eleven endplates (L1-S1) in the lumbar spine were evaluated for the presence of MCs, type, location, and size to determine MCs prevalence and distribution patterns. Disk degeneration was graded using a Pfirrmann scale. RESULTS MCs were present in 209 (47.3%) subjects and 593 (12.2%) endplates. Among these endplates, 84.1% (499) were type II, 9.1% (54) were type I, and 6.4% (38) were mixed MCs. Approximately 2/3 MCs were present in the lower lumbar spine and 44.9% of MCs were at the L5/S1 disk level. Most MCs (73.9%) involved both endplates of a disk. Greater age [odds ratio (OR)=2.44 for each 10-year increase, P |
| Databáze: | OpenAIRE |
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