Platinum(II) catalysts for highly enantioselective 1,6-enyne cycloisomerizations. synthetic, structural, and catalytic studies
| Autor: | Delphine Brissy, Hélène Jullien, Myriem Skander, Angela Marinetti, Pascal Retailleau |
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| Přispěvatelé: | Institut de Chimie des Substances Naturelles (ICSN), Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC) |
| Rok vydání: | 2009 |
| Předmět: |
Denticity
[SDV.BC]Life Sciences [q-bio]/Cellular Biology 010402 general chemistry 01 natural sciences Biochemistry Catalysis chemistry.chemical_compound Heterocyclic Compounds 1-Ring Cycloisomerization Organometallic Compounds Organic chemistry Physical and Theoretical Chemistry MESH: Cyclization Platinum Chiral auxiliary Enyne 010405 organic chemistry Organic Chemistry MESH: Platinum Enantioselective synthesis MESH: Organometallic Compounds Stereoisomerism MESH: Catalysis MESH: Stereoisomerism 0104 chemical sciences chemistry MESH: Heterocyclic Compounds 1-Ring Cyclization Alkynes Enantiomer Carbene MESH: Alkynes |
| Zdroj: | Organic Letters Organic Letters, American Chemical Society, 2009, 11 (10), pp.2137-9. ⟨10.1021/ol900724z⟩ |
| ISSN: | 1523-7052 1523-7060 |
| DOI: | 10.1021/ol900724z⟩ |
| Popis: | International audience; A new family of cyclometalated (N-heterocyclic carbene)-Pt(II) complexes bearing monodentate phosphines as ancillary ligands has been designed for use as precatalysts in 1,6-enyne cycloisomerization reactions. Highly enantioselective skeletal rearrangements of allylpropargyl-tosylamide derivatives have been developed by using (S)-Ph-Binepine as the chiral auxiliary. Enantiomeric excesses up to 97% have been obtained. |
| Databáze: | OpenAIRE |
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