Dry eye symptoms and impact on vision-related function across International Task Force guidelines severity levels in the United States
| Autor: | Stephen Montaquila, Thomas E. Croley, Laurie Barber, Vaishali Patel, Christopher Lievens, Jillian F. Ziemanski, Orsolya Lunacsek, Omid Khodai, Melissa McCart, Caroline Burk |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male 0301 basic medicine medicine.medical_specialty Visual acuity genetic structures Visual Acuity Vision-related function Signs and symptoms Severity of Illness Index Cornea 03 medical and health sciences 0302 clinical medicine lcsh:Ophthalmology Symptom relief Internal medicine medicine Humans Ocular Surface Disease Index Dry eye disease Aged Task force business.industry Mean age General Medicine Middle Aged United States eye diseases Ophthalmology Cross-Sectional Studies 030104 developmental biology lcsh:RE1-994 Tears Baseline characteristics Quality of Life 030221 ophthalmology & optometry Dry Eye Syndromes Female medicine.symptom Severity level International Task Force guidelines business Conjunctiva Research Article |
| Zdroj: | BMC Ophthalmology, Vol 18, Iss 1, Pp 1-9 (2018) BMC Ophthalmology |
| ISSN: | 1471-2415 |
| DOI: | 10.1186/s12886-018-0919-7 |
| Popis: | Background International Task Force (ITF) guidelines established a grading scheme to support treatment of dry eye disease based on clinical signs and symptoms. The purpose of this study was to assess the impact of dry eye on vision-related function across ITF severity levels using the Ocular Surface Disease Index (OSDI) questionnaire. Methods Non-interventional, cross-sectional study of prescription treatment-naïve dry eye patients seeking symptom relief at 10 ophthalmology and optometry practices. Clinicians assessed corneal and conjunctival staining, tear break-up time, Schirmer’s test (type I with anesthesia), and best-corrected visual acuity. Patients completed the OSDI questionnaire and OSDI overall and domain (Symptoms, Visual Function, and Environmental Triggers) scores were compared across ITF guidelines severity levels (1–4). Results Of 158 patients (mean age, 55 years) enrolled, 52 (33%) were ITF level 1, 54 (34%) ITF level 2, and 52 (33%) ITF levels 3/4 combined. No significant differences were observed in most baseline characteristics. Overall OSDI scores (mean [standard deviation]) were 26.5 [20.0] for ITF level 1, 33.8 [17.5] for ITF level 2, and 44.9 [26.1] for ITF level 3/4 cohorts (P |
| Databáze: | OpenAIRE |
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