Malignant ganglioglioma: case report and review of literature
| Autor: | Ryan DeMarchi, Suzy Abu-Abed, David G. Munoz, R. Loch Macdonald |
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| Rok vydání: | 2010 |
| Předmět: |
Male
Cancer Research medicine.medical_specialty Pathology Neurology Neurosurgery Ganglioglioma White matter Hematoma Glial Fibrillary Acidic Protein medicine Humans medicine.diagnostic_test Brain Neoplasms business.industry Magnetic resonance imaging Middle Aged medicine.disease Magnetic Resonance Imaging Ki-67 Antigen medicine.anatomical_structure ELAV Proteins Oncology Anaplastic Ganglioglioma Neurology (clinical) Headaches medicine.symptom Tomography X-Ray Computed business |
| Zdroj: | Journal of Neuro-Oncology. 101:311-318 |
| ISSN: | 1573-7373 0167-594X |
| DOI: | 10.1007/s11060-010-0248-z |
| Popis: | We report a case of de novo malignant ganglioglioma. A 61-year-old male presented with a 12-day history of headaches and general malaise. Pre-operative magnetic resonance imaging revealed an irregular enhancing mass in the left temporal lobe with associated dural enhancement and subacute subdural hematoma. The findings at surgery were of a vascular tumor intimately involving the surrounding white matter, with central necrosis. Histological and immunohistochemical studies showed an anaplastic ganglioglioma with World Health Organization grade IV characteristics. Gangliogliomas of the central nervous system are rare and are typified by a pediatric predilection and indolent behavior. A review of the de novo anaplastic and malignant gangliogliomas is presented. |
| Databáze: | OpenAIRE |
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