Inspiratory muscle training improves maximal inspiratory pressure and may assist weaning in older intubated patients: a randomised trial
| Autor: | Maria Celeste Vega Gomes, Rodrigo Gomes Vale, Juracy Correa Castro, Silvia Correa Bacelar, Cintia Biehl, Samária Ali Cader, Estélio Henrique Martin Dantas, Walter Eduardo Cabrera |
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| Jazyk: | angličtina |
| Předmět: |
Male
medicine.medical_specialty Time Factors Respiratory rate medicine.medical_treatment Pressure support ventilation Physical Therapy Sports Therapy and Rehabilitation Kaplan-Meier Estimate Weaning Spontaneous breathing trial law.invention Randomized controlled trial law Intensive care Outcome Assessment Health Care medicine Intubation Intratracheal Humans Physiotherapy Tidal volume Physical Therapy Modalities Aged Mechanical ventilation Aged 80 and over Inspiratory muscle training business.industry Respiration Respiratory Muscles Treatment Outcome Inhalation Physical therapy Female Respiration artificial business Respiratory Insufficiency Ventilator Weaning |
| Zdroj: | Journal of Physiotherapy. (3):171-177 |
| ISSN: | 1836-9553 |
| DOI: | 10.1016/S1836-9553(10)70022-9 |
| Popis: | Questions Does inspiratory muscle training improve maximal inspiratory pressure in intubated older people? Does it improve breathing pattern and time to wean from mechanical ventilation? Design Randomised trial with concealed allocation and intention-to-treat analysis. Participants 41 elderly, intubated adults who had been mechanically ventilated for at least 48 hr in an intensive care unit. Intervention The experimental group received usual care plus inspiratory muscle training using a threshold device, with an initial load of 30% of their maximal inspiratory pressure, increased by 10% (absolute) daily. Training was administered for 5 min, twice a day, 7 days a week from the commencement of weaning until extubation. The control group received usual care only. Outcome measures The primary outcome was the change in maximal inspiratory pressure during the weaning period. Secondary outcomes were the weaning time (ie, from commencement of pressure support ventilation to successful extubation), and the index of Tobin (ie, respiratory rate divided by tidal volume during a 1-min spontaneous breathing trial). Results Maximal inspiratory pressure increased significantly more in the experimental group than in the control group (MD 7.6 cmH 2 O, 95% CI 5.8 to 9.4). The index of Tobin decreased significantly more in the experimental group than in the control group (MD 8.3 br/min/L, 95% CI 2.9 to 13.7). In those who did not die or receive a tracheostomy, time to weaning was significantly shorter in the experimental group than in the control group (MD 1.7 days, 95% CI 0.4 to 3.0). Conclusions In intubated older people, inspiratory muscle training improves maximal inspiratory pressure and the index of Tobin, with a reduced weaning time in some patients. Trial registration NCT00922493. |
| Databáze: | OpenAIRE |
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