Facial nerve tractography: A new tool for the detection of perineural spread in parotid cancers
| Autor: | Alexandre Krainik, Félix Renard, René-Charles Rouchy, Sylvie Grand, Adrian Kastler, Maud Medici, Arnaud Attyé, Irène Troprès, Christian Righini |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Fractional anisotropy medicine Humans Radiology Nuclear Medicine and imaging Neoplasm Invasiveness Neuroradiology Aged business.industry Ultrasound General Medicine Middle Aged Facial nerve Magnetic Resonance Imaging Parotid Neoplasms Facial Nerve Diffusion Tensor Imaging Perineural spread Parotid cancer Parotid tumors Anisotropy Female Radiology business 030217 neurology & neurosurgery Tractography |
| Zdroj: | European radiology. 28(9) |
| ISSN: | 1432-1084 |
| Popis: | To determine whether facial nerve MR tractography is useful in detecting PeriNeural Spread in parotid cancers. Forty-five participants were enrolled. Thirty patients with surgically managed parotid tumors (15 malignant, 15 benign) were compared with 15 healthy volunteers. All of them had undergone 3T-MRI with diffusion acquisition and post-processing constrained spherical deconvolution-based tractography. Parameters of diffusion-weighted sequences were b-value 1,000 s/mm2, 32 directions. Two radiologists performed a blinded visual reading of tractographic maps and graded the facial nerve average pathlength and fractional anisotropy (FA). We also compared diagnostic accuracy of tractography with morphological MRI sequences to detect PeriNeural Spread. Non-parametric methods were used. Average pathlength was significantly higher in cases with PeriNeural Spread (39.86 mm [Quartile1: 36.27; Quartile3: 51.19]) versus cases without (16.23 mm [12.90; 24.90]), p |
| Databáze: | OpenAIRE |
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