Phaeohyphomycosis due to Exophiala xenobiotica as a cause of fungal arthritis in an HIV-infected patient

Autor: Laurent Benard, Dea Garcia-Hermoso, Christophe Michau, Florent Morio, Sybren de Hoog, Mohammad Javad Najafzadeh, Jean-Yves Le Berre
Přispěvatelé: Centre hospitalier universitaire de Nantes (CHU Nantes), Université de Nantes (UN), Centre hospitalier de Saint-Nazaire, Centre National de Référence des Mycoses invasives et antifongiques - Mycologie moléculaire (CNRMA), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Mashhad University of Medical Sciences, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Male
MESH: Sequence Analysis
DNA

Black yeast
black yeast
molecular identification
HIV Infections
Exophiala xenobiotica
Subcutaneous Tissue
MESH: Subcutaneous Tissue
Common species
Exophiala
DNA
Fungal

Mycological Typing Techniques
[SDV.MP.MYC]Life Sciences [q-bio]/Microbiology and Parasitology/Mycology
0303 health sciences
MESH: Middle Aged
biology
MESH: AIDS-Related Opportunistic Infections
General Medicine
MESH: HIV Infections
Middle Aged
3. Good health
Phaeohyphomycosis
Phenotype
Infectious Diseases
arthritis
Molecular phylogenetics
MESH: Immune Reconstitution Inflammatory Syndrome
MESH: Arthritis
Infectious

MESH: Phaeohyphomycosis
medicine.medical_specialty
AIDS-Related Opportunistic Infections
Molecular Sequence Data
MESH: Phenotype
Microbiology
03 medical and health sciences
Molecular genetics
MESH: Mycological Typing Techniques
medicine
Humans
phaeohyphomycosis
030304 developmental biology
Arthritis
Infectious

MESH: Humans
MESH: Molecular Sequence Data
030306 microbiology
MESH: Exophiala
Exophiala jeanselmei
Sequence Analysis
DNA

biology.organism_classification
medicine.disease
immune reconstitution inflammatory syndrome
MESH: Male
MESH: DNA
Fungal
Zdroj: Medical Mycology
Medical Mycology, Oxford University Press, 2012, 50 (5), pp.513-517. ⟨10.3109/13693786.2011.648218⟩
Medical Mycology, 50(5), 513-517. Informa Healthcare
Medical Mycology, 2012, 50 (5), pp.513-517. ⟨10.3109/13693786.2011.648218⟩
ISSN: 1369-3786
1365-280X
DOI: 10.3109/13693786.2011.648218⟩
Popis: International audience; Black yeasts including Exophiala species are increasingly recognized as agents of human disease. In recent years, progress in molecular phylogeny and taxonomy of the genus Exophiala has led to the description of numerous novel species. The 'classical' but highly variable species Exophiala jeanselmei was split into a number of morphological siblings, which, however, were phylogenetically and clinically remote from each other. E. jeanselmei was restricted to an uncommon species causing subcutaneous infections. Hence only limited information is available on the segregants, among which is E. xenobiotica. We describe a case of an HIV-patient presenting with fungal arthritis and subcutaneous nodules caused by the latter species, which was identified by means of phenotypic and molecular methods.
Databáze: OpenAIRE