Reconstruction of Aplasia Cutis Congenita of the Trunk in a Newborn Infant Using Acellular Allogenic Dermal Graft and Cultured Epithelial Autografts
| Autor: | Richard Simman, Cedric J. Priebe, Marcia Simon |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Thorax
medicine.medical_specialty Silver sulfadiazine Transplantation Autologous Aplasia cutis congenita Lesion Dermis Ectodermal Dysplasia Abdomen medicine Humans Fetal Death Cells Cultured Skin Artificial integumentary system business.industry Infant Newborn Epithelial Cells Plastic Surgery Procedures Trunk Surgery Plastic surgery medicine.anatomical_structure Scalp Female medicine.symptom business medicine.drug |
| Zdroj: | Annals of Plastic Surgery. 44:451-454 |
| ISSN: | 0148-7043 |
| Popis: | Aplasia cutis congenita, a congenital condition characterized by the absence of all skin layers, occurs mostly on the scalp, but may also involve the trunk and extremities. Conservative treatment using silver sulfadiazine with daily dressing change has been recommended to avoid donor site morbidity and operative risks to the neonate who may have other congenital defects. Others have proposed early surgical intervention to prevent problems associated with delayed wound healing. In this case of a newborn, the authors used an alternative therapy to avoid delayed wound healing and multiple surgical interventions. During one operative procedure, a 130-cm2 lesion on the trunk was covered with allogeneic dermis and cultured epithelial autografts (CEAs). After 2.5 weeks and with three additional applications of CEAs at bedside, 90% of the wound had healed. At 27 months, the grafted area was smooth, and pliable with normal skin texture. Simman R, Priebe Jr CJ, Simon M. Reconstruction of aplasia cutis congenita of the trunk in a newborn infant using acellular allogenic dermal graft and cultured epithelial autografts. Ann Plast Surg 2000;44:451-454 |
| Databáze: | OpenAIRE |
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