Histopathological findings in the advanced natural evolution of the SARS-CoV-2 infection
| Autor: | Radu Lucian Buzulica, Razvan Ene, Ovidiu Mircea Gheorghe, Radu Vasile Iman, Laurentiu Mogoanta, Liliana Stanca, Simona Daniela Neamtu, Samir Kumar-Singh, Mihail Constantin Ceausu, Andreea Elena Cîrstea, Daniel Pirici |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Embryology medicine.medical_specialty Pneumonia Viral Autopsy Case Report Kidney Virus Pathology and Forensic Medicine Betacoronavirus COVID-19 Testing Internal medicine medicine Humans COVID-19 pneumonia Biology Pathological Lung Pancreas Pandemics biology advanced natural evolution business.industry Clinical Laboratory Techniques Reverse Transcriptase Polymerase Chain Reaction Romania SARS-CoV-2 Myocardium SARS-CoV-2 infection COVID-19 Thrombosis Cell Biology General Medicine biology.organism_classification medicine.disease Reverse transcription polymerase chain reaction Pneumonia medicine.anatomical_structure Liver histopathology Female Vasculitis business Coronavirus Infections Developmental Biology |
| Zdroj: | Romanian Journal of Morphology and Embryology ROMANIAN JOURNAL OF MORPHOLOGY AND EMBRYOLOGY |
| ISSN: | 2066-8279 1220-0522 |
| Popis: | We are reporting a case of natural evolution and pathological data from a young person that was diagnosed with coronavirus disease 2019 (COVID-19). All data has been collected from the autopsy of a 30-year-old female, which was performed by the Department of Forensic Medicine from Emergency County Hospital, Drobeta Turnu Severin, Mehedinti County, Romania. The infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was confirmed by reverse transcription polymerase chain reaction (RT-PCR) on the lung tissue which was obtained during autopsy. This case provides the opportunity to study the natural evolution of COVID-19 pneumonia in a young person with clinical signs of pneumonia but without associated comorbidities. The patient had not received any treatment. The histopathological examination of the lung revealed a process of productive proliferation, proteinaceous and fibrin-macrophagic interalveolar spaces exudate, and lesions consistent with vasculitis. In the heart, we identified a cardiac thrombus. These changes are likely to suggest an advanced natural evolution of SARS-CoV-2 virus infection. |
| Databáze: | OpenAIRE |
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