High prevalence of cardiovascular risk in patients with toxic oil syndrome: a comparative study using the general Spanish population
| Autor: | Beatriz Braun Saro, María Luisa García de Aguinaga, Francisco Hernandez, Eva Estirado de Cabo, Ignacio Abaitua Borda, Carmen Suarez Alvarez, Rafael Sánchez, María del Mar Plaza Cano, Manuel Posada de la Paz |
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| Rok vydání: | 2006 |
| Předmět: |
Adult
Male medicine.medical_specialty Population Hypercholesterolemia Protective factor Food Contamination Comorbidity Disease Outbreaks Fatty Acids Monounsaturated Risk Factors Diabetes mellitus Internal medicine Internal Medicine medicine Diabetes Mellitus Prevalence Humans Plant Oils education Aged Metabolic Syndrome education.field_of_study business.industry Poisoning Middle Aged medicine.disease Obesity Causality Blood pressure Cardiovascular Diseases Spain Case-Control Studies Cohort Hypertension Physical therapy Female Rapeseed Oil Metabolic syndrome business Toxic oil syndrome |
| Zdroj: | European journal of internal medicine. 19(1) |
| ISSN: | 1879-0828 |
| Popis: | Background The objective of this study was to compare current prevalence of major cardiovascular risk factors (CRF) between a cohort of patients affected by the toxic oil syndrome (TOS) epidemic, which occurred in Spain in 1981, and the unaffected Spanish population. Methods This was a case-referent study covering 1276 TOS cases and a referent population of 2843 (aged 35–65 years) using data collected from 1996 to 2003. Study variables were high blood pressure, hyperglycemia, dyslipemia, obesity, and metabolic syndrome. Smoking habit, alcohol intake, family and personal history of ischemic heart disease, as well as a personal history of cerebrovascular disease were also assessed in TOS patients. Results Compared to the general population, TOS patients registered a threefold rise in prevalence of diabetes, a 2.57-fold increase in hypertension, a 1.38-fold increase in total hypercholesterolemia, a 1.20-fold increase in hyper-LDL-cholesterolemia, and a high prevalence of metabolic syndrome (35% versus 25%). Nevertheless, the prevalence of hypo-HDL-cholesterolemia was significantly lower in those affected by TOS. No differences were found for other CRFs. Conclusion Compared to the general population, cases display a much higher prevalence of all major CRFs. However, an increase in HDL-cholesterol protective factor is in evidence for the first time. |
| Databáze: | OpenAIRE |
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