Anatomopathologic Subtypes of Endometrial Carcinoma: Case-Control Study of 122 Cases. Epidemiology and Ultrasound
Autor: | Engels, Luis Sanfrutos, B Bueno, Orensanz I, Tirso Pérez-Medina, de la Fuente J, Salazar F, José Bajo-Arenas |
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Rok vydání: | 2007 |
Předmět: |
medicine.medical_specialty
Pathology endocrine system diseases business.industry Ultrasound Case-control study Cancer Endometrial Carcinomas lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens medicine.disease lcsh:RC254-282 female genital diseases and pregnancy complications Exact test Oncology Older patients Epidemiology Carcinoma medicine business |
Zdroj: | Clinical Medicine Insights: Oncology, Vol 1 (2007) |
ISSN: | 1177-9314 |
DOI: | 10.4137/cmo.s367 |
Popis: | Objective To determine the epidemiological and sonographic characteristics of patients with endometrial carcinoma of endometrioid and non-endometrioid subtype to analyse if any differences can be observed between the groups. Study design A case-control study was performed considering 122 patients with endometrial carcinoma where 96 (78.69%) had endometrioid carcinomas (controls) and 26 (21.31%) had non-endometrioid carcinomas (cases). Epidemiological, clinical, and sonographic variables (endometrial thickness and sonographic suspicion of myometrial invasion of the tumour) were analysed. Qualitative variables were studied with the Chi-square test and the Fisher's exact test and quantitative variables with the t test. A value of p < 0.05 was considered statistically significant. Results Tumours of the non-endometrioid type are observed in older patients (p = 0.003) and frequently show a higher sonographic tumoral invasion (p = 0.0036). Conclusions This study supports previous observations that non-endometrioid endometrial carcinomas present at older ages and provides new data that non-endometrioid carcinoma more frequently show sonographic images compatible with myometrial invasion. |
Databáze: | OpenAIRE |
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