Congenital varicella syndrome: case with isolated brain damage
| Autor: | Alexander A. Karparov, Petia Dimova |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Male
Developmental Disabilities Congenital Varicella Syndrome Disease Serology 03 medical and health sciences Epilepsy 0302 clinical medicine Chickenpox 030225 pediatrics medicine Humans Child Intracerebral hemorrhage Pregnancy medicine.diagnostic_test business.industry Brain Magnetic resonance imaging Electroencephalography Isolated brain medicine.disease Magnetic Resonance Imaging Fetal Diseases Anesthesia Pediatrics Perinatology and Child Health Epilepsy Generalized Neurology (clinical) business Tomography X-Ray Computed 030217 neurology & neurosurgery |
| Zdroj: | Journal of child neurology. 16(8) |
| ISSN: | 0883-0738 |
| Popis: | We report a case of congenital varicella syndrome after maternal infection during the 10th week of pregnancy. None of the typical abnormalities were manifested at birth; however, the child experienced neonatal tonic convulsions that evolved to refractory focal epilepsy with adversive, complex partial, and secondarily generalized seizures. At the age of 5 years, after a prolonged generalized seizure following cranial trauma, cranial computed tomography (CT) was performed. It led to the misdiagnosis of post-traumatic intracerebral hemorrhage. Afterwards, because of persistent seizures and developmental delay with mild or slight intellectual deficit, the next CT and magnetic resonance imaging (MRI) investigation at 8 years of age disclosed massive malformation of the left cerebral hemisphere. The serologic evidence of varicella-zoster virus-specific IgG antibodies without a history of varicella disease after birth and maternal infection during early pregnancy were crucial to diagnosing the rare syndrome of congenital varicella consisting of isolated brain damage. (J Child Neurol 2001;16:595-597). |
| Databáze: | OpenAIRE |
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