Validating screening tools for depression in stroke and transient ischemic attack patients
| Autor: | Andrew M. Demchuk, Scott B. Patten, Shelagh B. Coutts, Callie Atta, Michael D. Hill, Laura Blaikie, Kirsten M. Fiest, Joey C. Prisnie, Eric E. Smith, Nathalie Jette, Andrew G. M. Bulloch |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male Canada medicine.medical_specialty Patient Health Questionnaire Hospital Anxiety and Depression Scale Sensitivity and Specificity 03 medical and health sciences 0302 clinical medicine Surveys and Questionnaires medicine Humans Mass Screening Screening tool Stroke Depression (differential diagnoses) Aged Depressive Disorder Major Depression business.industry Middle Aged medicine.disease Depression screening Mental health 030227 psychiatry Diagnostic and Statistical Manual of Mental Disorders Psychiatry and Mental health Ischemic Attack Transient Physical therapy Female Geriatric Depression Scale business 030217 neurology & neurosurgery |
| Zdroj: | The International Journal of Psychiatry in Medicine. 51:262-277 |
| ISSN: | 1541-3527 0091-2174 |
| DOI: | 10.1177/0091217416652616 |
| Popis: | Objective The best screening questionnaires for detecting post-stroke depression have not been identified. We aimed to validate four commonly used depression screening tools in stroke and transient ischemic attack patients. Methods Consecutive stroke and transient ischemic attack patients visiting an outpatient stroke clinic in Calgary, Alberta (Canada) completed a demographic questionnaire and four depression screening tools: Patient Health Questionnaire (PHQ)-9, PHQ-2, Hospital Anxiety and Depression Scale (HADS-D), and Geriatric Depression Scale (GDS-15). Participants then completed the Structured Clinical Interview for DSM-IV (SCID), the gold-standard for diagnosing major depression. The questionnaires were validated against the SCID and sensitivity and specificity were calculated at various cut-points. Optimal cut-points for each questionnaire were determined using receiver-operating curve analyses. Results Among 122 participants, 59.5% were diagnosed with stroke and 40.5% with transient ischemic attack. The point prevalence of SCID-diagnosed current major depression was 9.8%. At the optimal cut-points, the sensitivity and specificity for each screening tool were as follows: PHQ-9 (sensitivity: 81.8%, specificity: 97.1%), PHQ-2 (sensitivity: 75.0%, specificity: 96.3%), HADS-D (sensitivity: 63.6%, specificity: 98.1%), and GDS-15 (sensitivity: 45.5%, specificity: 84.8%). Areas under the receiver operating characteristic curves were as follows: PHQ-9 86.6%, PHQ-2 86.7%, HADS-D 85.9%, and GDS-15 66.3%. Conclusions The PHQ-2 and PHQ-9 are both suitable depression screening tools, taking less than 5 minutes to complete. The HADS-D does not appear to have any advantage over the PHQ-based scales, even though it was designed specifically for medically ill populations. The GDS-15 cannot be recommended for general use in a stroke clinic based on this study as it had worse discrimination due to low sensitivity. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|