Acute coronary syndrome antiplatelet alternatives in clopidogrel allergy
| Autor: | Anastasia M. Manchette, James L. Januzzi, Adrienne G. Drucker |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male Allergy medicine.medical_specialty Acute coronary syndrome Ticagrelor Adenosine Ticlopidine Drug Hypersensitivity Internal medicine medicine Humans Pharmacology (medical) In patient cardiovascular diseases Acute Coronary Syndrome Aged Retrospective Studies Retrospective review business.industry Clopidogrel medicine.disease Anesthesia Female business Platelet Aggregation Inhibitors circulatory and respiratory physiology medicine.drug |
| Zdroj: | Pharmacotherapy. 34(8) |
| ISSN: | 1875-9114 |
| Popis: | No published information exists to support the safe use of ticagrelor in patients with a clopidogrel allergy. This study involved an institutional review board-approved retrospective review of patients with a documented clopidogrel allergy who subsequently received ticagrelor between July 2011 and February 2014. We report the cases of two patients with a history of hypersensitivity to clopidogrel in whom ticagrelor was used successfully without documented incident. In addition, principles suggesting a lack of cross-sensitivity between ticagrelor and clopidogrel are reviewed. These cases combined with theoretical evidence support the use of ticagrelor in patients with hypersensitivity to clopidogrel. |
| Databáze: | OpenAIRE |
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