Prolactinoma in a Dog
| Autor: | Cosio, Cristina, Sartori, Elena, Garatti, Marcello, Luccardini, Lorenzo, Grinwis, G C M, Kooistra, Hans S, Fracassi, Federico, Veterinair Pathologisch Diagnostisch Cnt, PB AVM, dPB CR |
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| Přispěvatelé: | Cosio, Cristina, Sartori, Elena, Garatti, Marcello, Luccardini, Lorenzo, Grinwis, G. C. M., Kooistra, Hans S., Fracassi, Federico |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Adenoma
Male medicine.medical_specialty Galactorrhea Pituitary gland prolactin dogs Tomography Scanners X-Ray Computed Pituitary disease gynecomastia 040301 veterinary sciences 030209 endocrinology & metabolism Pituitary neoplasm paraneoplastic syndrome 0403 veterinary science 03 medical and health sciences Fatal Outcome 0302 clinical medicine galactorrhea Internal medicine medicine Enlarged pituitary gland Animals Pituitary Neoplasms Ergolines Prolactinoma General Veterinary business.industry Pituitary tumors 04 agricultural and veterinary sciences endocrine diseases medicine.disease Prolactin neoplasia medicine.anatomical_structure Endocrinology prolactinoma Dopamine Agonists dog Veterinary (all) cabergoline endocrine disease medicine.symptom business |
| Zdroj: | Veterinary Pathology, 54(6), 972. SAGE Publications Ltd |
| ISSN: | 0300-9858 |
| Popis: | A 12-year-old male Yorkshire Terrier was presented because of decreased appetite. Physical examination revealed mammary gland swelling and galactorrhea. Contrast-enhanced computed tomographic scanning of the skull indicated an enlarged pituitary gland, compatible with a pituitary tumor. The serum prolactin concentration was markedly elevated. One week after the start of treatment with the dopamine agonist cabergoline, the serum prolactin concentration normalized and the galactorrhea resolved. Cabergoline was administered for approximately 4 months and then discontinued. Subsequently, serum prolactin concentration increased again, and mammary gland swelling and galactorrhea reappeared. The dog was euthanized 10 months after the first detection of the galactorrhea because of problems not directly related to pituitary disease. Postmortem examination revealed an infiltrative adenoma of the pituitary gland with immunolabeling for prolactin. The clinical and histopathologic findings indicated the diagnosis of a functional prolactinoma in a male dog. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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