Diabetes primary prevention program: new insights from data analysis of recruitment period
| Autor: | Juan Pablo Antonio Ricart, Peter Kronsbein, Alberto Omar Ricart, Marcelo Bourgeois, Eduardo Spinedi, Silvia García, Gabriel Fantuzzi, Camilo Martínez, Graciela Etchegoyen, Juan José Gagliardino, Florencia Suárez-Crivaro, Lorena Gonzalez, Matías Ré, Jorge A. Martínez, Jorge Federico Elgart, Cecilia Giampieri, Julieta María Angelini |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Blood Glucose
Male endocrine system diseases Dyslipidemia in pre-diabetes Endocrinology Diabetes and Metabolism BUENOS AIRES Type 2 diabetes Medicina Clínica Impaired glucose tolerance 0302 clinical medicine Endocrinology Surveys and Questionnaires purl.org/becyt/ford/3.2 [https] PREDIABETES Mass Screening 030212 general & internal medicine Prediabetes Prospective Studies education.field_of_study FINDRISC score Middle Aged Prognosis Primary Prevention purl.org/becyt/ford/3 [https] Female Medicina Critica y de Emergencia Pre-diabetes RECRUITMENT medicine.medical_specialty CIENCIAS MÉDICAS Y DE LA SALUD Population Argentina Diabetes primary prevention 030209 endocrinology & metabolism Prediabetic State 03 medical and health sciences Insulin resistance Diabetes mellitus Internal medicine Glucose Intolerance Internal Medicine medicine OGTT Humans education Glycated Hemoglobin business.industry nutritional and metabolic diseases Glucose Tolerance Test medicine.disease Impaired fasting glucose PREVENTION Diabetes Mellitus Type 2 Ciencias Médicas Insulin Resistance business Dyslipidemia Biomarkers Follow-Up Studies |
| Zdroj: | CONICET Digital (CONICET) Consejo Nacional de Investigaciones Científicas y Técnicas instacron:CONICET |
| Popis: | Background Primary Prevention of Diabetes Program in Buenos Aires Province evaluates the effectiveness of adopting healthy lifestyle to prevent type 2 diabetes (T2D) in people at high risk of developing it. We aimed to present preliminary data analysis of FINDRISC and laboratory measurements taken during recruitment of people for the Primary Prevention of Diabetes Program in Buenos Aires Province in the cities of La Plata, Berisso, and Ensenada, Argentina. Methods People were recruited through population approach (house-to-house survey by FINDRISC in randomized areas) and opportunistic approach (FINDRISC completed by participants during consultations for nonrelated prediabetes/diabetes symptoms in public and private primary care centres of cities involved). In people with FINDRISC score ≥ 13 points, we evaluated blood concentrations of HbA1c , creatinine, lipids, and an oral glucose tolerance test (OGTT). Results Approximately 3415 individuals completed the FINDRISC populational survey and 344 the opportunistic survey; 43% of the 2 groups scored over 13 points; 2.8 and 75.4% of them, respectively, took the prescribed OGTT. Approximately 53.7% of the OGTT showed normal values and 5.2% unknown T2D. The remaining cases showed 69.5% impaired fasting glucose, 13.6% impaired glucose tolerance, and 16.9% both impairments. HbA1c values showed significant differences compared with normal glucose tolerance (4.96 ± 0.43%), prediabetes (5.28 ± 0.51%), and T2D (5.60 ± 0.51%). Participants with prediabetes and T2D showed a predominant increase in low-density lipoprotein-cholesterol values. In prediabetes, >50% showed insulin resistance. Conclusions People with prediabetes/T2D had dyslipidemia associated with insulin resistance, which promotes the development of T2D and cardiovascular disease. Thus, it merits its appropriate treatment. Centro de Endocrinología Experimental y Aplicada Instituto de Investigaciones en Humanidades y Ciencias Sociales |
| Databáze: | OpenAIRE |
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