Diffuse bilateral cerebral astrocytomas with atypical neuroimaging studies
| Autor: | Lisa R. Rogers, Weinstein Ma, Estes Ml, Cairncross Jg, Strachan T |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Adolescent Brain tumor Astrocytoma Basal Ganglia Corpus Callosum Diagnosis Differential Leukoencephalopathy Clinical Protocols Neuroimaging Glioma medicine Humans neoplasms Aged Retrospective Studies Cerebral Cortex medicine.diagnostic_test Brain Neoplasms business.industry Multiple sclerosis Magnetic resonance imaging Middle Aged medicine.disease Combined Modality Therapy Magnetic Resonance Imaging nervous system diseases Female Glioblastoma Tomography X-Ray Computed business Brain Stem Anaplastic astrocytoma |
| Zdroj: | Journal of Neurosurgery. 81:817-821 |
| ISSN: | 0022-3085 |
| Popis: | ✓ The authors describe the clinical behavior of eight patients with cerebral astrocytomas, in whom computerized tomography (CT) or magnetic resonance (MR) imaging of the brain was characterized by diffuse bilateral cerebral hemisphere tissue density abnormalities and minimal focal mass effect. Five patients were newly diagnosed, and three others had been treated for focal low-grade astrocytoma. Histological diagnoses included anaplastic astrocytoma (three patients), low-grade astrocytoma (three patients), glioblastoma (one patient), and gliosis with later development of glioblastoma (one patient). In five patients, brain tumor was not suspected from the neuroimaging studies, the findings of which were mistaken for radiation leukoencephalopathy, vasogenic edema, or multiple sclerosis. Serial CT scans or MR images undertaken over intervals of 3 to 184 weeks showed progression of abnormal tissue densities in seven patients and multifocal contrast-enhancing masses developed on CT scan in two patients. An autopsy in each of four patients showed diffuse cerebral infiltration by astrocytoma. It is concluded that neuroimaging studies in some patients with diffusely infiltrating cerebral astrocytoma are atypical for neoplasm and can be mistaken for other diseases, especially those that predominantly affect cerebral hemisphere white matter. |
| Databáze: | OpenAIRE |
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