Antifeedant Activities of Lignans from Stem Bark of Zanthoxylum armatum DC. against Tribolium castaneum
| Autor: | Zhen-Yang Chen, Shu-Shan Du, Zhi-Wei Deng, Yang Wang, Zhe Zhang, Zhu-Feng Geng, Wen-Juan Zhang, Ju-Qin Cao, Shan-Shan Guo, Xue Pang |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Zanthoxylum
Phytochemicals Pharmaceutical Science Positive control chemical constituents 01 natural sciences Lignans Article Methylenedioxy antifeedant activity Analytical Chemistry lcsh:QD241-441 Tribolium castaneum chemistry.chemical_compound lcsh:Organic chemistry Drug Discovery Plant Bark Animals Spectral analysis Physical and Theoretical Chemistry EC50 Tribolium Stem bark Molecular Structure Plant Stems biology Traditional medicine Plant Extracts 010405 organic chemistry Chemistry Organic Chemistry Zanthoxylum armatum methylenedioxy biology.organism_classification 0104 chemical sciences 010404 medicinal & biomolecular chemistry Chemistry (miscellaneous) Molecular Medicine |
| Zdroj: | Molecules; Volume 23; Issue 3; Pages: 617 Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry Molecules, Vol 23, Iss 3, p 617 (2018) |
| ISSN: | 1420-3049 |
| DOI: | 10.3390/molecules23030617 |
| Popis: | The speciation of a methanolic extract of Zanthoxylum armatum stem bark has enabled the isolation and characterization of 11 known lignans. Among them, five compounds (6, 8–11) are reported in this plant for the first time. All of the chemical structures were elucidated on the basis of NMR spectral analysis. Additionally, their antifeedant activities against Tribolium castaneum were evaluated scientifically. Among them, asarinin (1), with an EC50 of 25.64 ppm, exhibited a much stronger antifeedant activity than the positive control, toosendanin (EC50 = 71.69 ppm). Moreover, fargesin (2), horsfieldin (3), and magnolone (10), with EC50 values of 63.24, 68.39, and 78.37 ppm, showed almost the same antifeedant activity as the positive control. From the perspective of structure-effectiveness relationship, compounds with the chemical group of methylenedioxy exhibited higher antifeedant activities and have potential to be developed into novel antifeedants or potential lead compounds to protect food and crops in storage. |
| Databáze: | OpenAIRE |
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