Microcystin concentrations and liver histopathology in Clarias gariepinus and Oreochromis mossambicus from three impacted rivers flowing into a hyper-eutrophic freshwater system: A pilot study
| Autor: | Isaac T. Rampedi, Annemariè Avenant-Oldewage, Vimbai Mhuka, Mathew Muzi Nindi, Lee-Ann S. Modley, Cobus van Dyk |
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| Rok vydání: | 2019 |
| Předmět: |
Clarias gariepinus
Oreochromis mossambicus Veterinary medicine Microcystins Health Toxicology and Mutagenesis Pilot Projects Microcystin-LR Microcystin 010501 environmental sciences Biology Toxicology 01 natural sciences Algal bloom South Africa 03 medical and health sciences chemistry.chemical_compound Rivers Species Specificity polycyclic compounds Animals Catfishes 030304 developmental biology 0105 earth and related environmental sciences Pharmacology chemistry.chemical_classification 0303 health sciences Hepatotoxin General Medicine Eutrophication biology.organism_classification Bioaccumulation Liver chemistry Marine Toxins Water Pollutants Chemical Environmental Monitoring Tilapia |
| Zdroj: | Environmental Toxicology and Pharmacology. 71:103222 |
| ISSN: | 1382-6689 |
| DOI: | 10.1016/j.etap.2019.103222 |
| Popis: | The Roodeplaat Dam and its three inflowing rivers are highly impacted by surrounding anthropogenic activities. The system is hyper-eutrophic and characterized by seasonal algal blooms and previous studies have reported levels of the hepatotoxin microcystin in the water of the impoundment. Limited information is available on the microcystin concentrations in the inflowing rivers and no information is available on the bioaccumulated levels and potential health effects in fish inhabiting these rivers. The aim of this study was to do a histopathological assessment and to determine the concentrations of bioaccumulated microcystins in the livers of two indicator fish species Clarias gariepinus and Oreochromis mossambicus. The results showed that the two species bioaccumulate microcystins at different concentrations and that their hepatic health response varied. The liver index was significantly higher for C. gariepinus compared to O. mossambicus. No significant positive correlation was found between the bioaccumulated microcystin levels and the liver histology index. It is recommended that this pilot study be followed by a controlled exposure study to confirm a possible cause and effect relationship between microcystin exposure and the specific liver alterations identified. |
| Databáze: | OpenAIRE |
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