Enteroglucagon and substance P-like immunoreactivity in argentaffin and argyrophil rectal carcinoids
| Autor: | G. Lundqvist, Portela-Gomes Gm, E. Wilander, V. Skoog, L. Grimelius |
|---|---|
| Rok vydání: | 1977 |
| Předmět: |
endocrine system
medicine.medical_specialty Pathology medicine.diagnostic_test Chemistry Rectal Neoplasms Immunocytochemistry Rectum Fluorescent Antibody Technique Enteroglucagon Substance P Carcinoid Tumor Immunofluorescence Glucagon Pathology and Forensic Medicine Trypsin like enzyme chemistry.chemical_compound Microscopy Electron Endocrinology medicine.anatomical_structure Argentaffin Internal medicine medicine Humans |
| Zdroj: | Virchows Archiv. B, Cell pathology. 25(2) |
| Popis: | A specific immunofluorescence for enteroglucagon or substance P or for both hormones was demonstrated in nine out of 12 examined rectal carcinoids. One tumor was argentaffin, contained ultrastructurally pleomorphic granules of the entero-chromaffin cell type, and showed immunofluorescence for substance P. The rest were non-argentaffin but were argyrophil with the Grimelius technique and contained round granules. The argyrophil carcinoids were immunoreactive to one or both hormones in eight cases and not fluorescent in three cases. In two of the non-argentaffin carcinoids a small number of argyrophil cells was found with the method of Sevier-Munger. |
| Databáze: | OpenAIRE |
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