Age differences and stress ulcer in the rat
| Autor: | George P. Vincent, Kile E. Isom, William P. Paré |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
Male
Restraint Physical Aging medicine.medical_specialty Supine position Gastroenterology Arts and Humanities (miscellaneous) Age groups Internal medicine medicine Animals Humans Stomach Ulcer Total acid Ligation Pylorus General Psychology Gastric Juice Age differences business.industry Stress ulcer Gastric Acidity Determination medicine.disease digestive system diseases Rats Surgery Cold Temperature medicine.anatomical_structure Gastric Mucosa Gastric acid Geriatrics and Gerontology business Stress Psychological |
| Zdroj: | Experimental Aging Research. 5:31-42 |
| ISSN: | 1096-4657 0361-073X |
| DOI: | 10.1080/03610737908257186 |
| Popis: | Rats 2-, 7- and 12- mo. old were exposed to supine body restraint plus cold (5°C) for 3 hr. The mean cumulative length of lesions for the 2-, 7-, and 12 mo. old rats was 22.0, 43.0 and 16.0 mm. respectively. The same experimental design was used in a second study, but the pylorus was ligated prior to restraint. Total acid output/hr. was 134.6, 178.2, and 64.7 μEq/60 min. respectively for the three age groups. Older rats were not more susceptible to stress-ulcer and gastric acid was not significantly related to degree of ulceration. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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