Varicella zoster virus acute retinal necrosis following eye contusion: case report
| Autor: | Pavel Diblik, Eva Říhová, Pavel Kuthan, Bohdana Kalvodová, P Svozílková, Zdeněk Kovařík |
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| Rok vydání: | 2005 |
| Předmět: |
Male
Herpesvirus 3 Human genetic structures Contusions Case Report Ocular trauma Disease medicine.disease_cause Antiviral Agents Herpes Zoster Eye injuries lcsh:Infectious and parasitic diseases acute retinal necrosis corticosteroids Eye Injuries Adrenal Cortex Hormones Virology Virus latency medicine Animals Humans Vasoconstrictor Agents lcsh:RC109-216 contusion varicella zoster virus business.industry Varicella zoster virus Retinal Necrosis Syndrome Acute Middle Aged medicine.disease eye diseases Virus Latency Infectious Diseases Acute retinal necrosis Ocular ischemic syndrome sense organs acyclovir business Eye contusion |
| Zdroj: | Virology Journal Virology Journal, Vol 2, Iss 1, p 77 (2005) |
| ISSN: | 1743-422X |
| Popis: | Background Acute retinal necrosis is a sight-threatening disease caused by the group of herpesviruses. The aim of this paper is to report a case of acute retinal necrosis following ocular trauma in a patient initially treated with vaso-active drugs and corticosteroids for presumed ocular ischemic syndrome. Case presentation A 51-years-old otherwise healthy man, who suffered from sudden visual loss in the left eye following contusion, was commenced on vaso-active drugs and systemic corticosteroids for suspected ocular ischemic syndrome with extensive swelling of the optic disc and macular edema. Subsequently, vision in the initially uninvolved right eye decreased. Polymerase chain reaction of vitreous samples and retinal biopsy confirmed varicella zoster virus. Despite intensive treatment with intravenous antiviral medication, the patient became completely blind in both eyes. Conclusion Initial treatment of acute, unexplained visual decrease with systemic corticosteroids may lead to visual loss in patients with developing acute retinal necrosis. Ocular trauma could have induced and corticosteroid treatment promoted reactivation of a latent viral infection in our patient. |
| Databáze: | OpenAIRE |
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