The role of NK cells in fighting the virus infection and sepsis
| Autor: | Suna Cai, Qi Li, Lu Ma, Hui Yang, Hourong Peng, Ting Huyan |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_treatment
Cell Review medicine.disease_cause Virus Sepsis Immune system medicine Humans Coronavirus Innate immune system business.industry Mechanism (biology) SARS-CoV-2 COVID-19 General Medicine Immunotherapy medicine.disease Killer Cells Natural medicine.anatomical_structure Viral infection Immunology Host-Pathogen Interactions Natural killer cells business |
| Zdroj: | International Journal of Medical Sciences |
| ISSN: | 1449-1907 |
| Popis: | Natural killer cells, one of the important types of innate immune cells, play a pivotal role in the antiviral process in vivo. It has been shown that increasing NK cell activity may promote the alleviation of viral infections, even severe infection-induced sepsis. Given the current state of the novel coronavirus (SARS-CoV-2) global pandemic, clarifying the anti-viral function of NK cells would be helpful for revealing the mechanism of host immune responses and decipher the progression of COVID-19 and providing important clues for combating this pandemic. In this review, we summarize the roles of NK cells in viral infection and sepsis as well as the potential possibilities of NK cell-based immunotherapy for treating COVID-19. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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