Rising Incidence of Paediatric Inflammatory Bowel Disease in Canterbury, New Zealand, 1996-2015
| Autor: | Andrew S. Day, Richard B. Gearry, Robert N Lopez, Laura Appleton |
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| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Adolescent Databases Factual Disease Inflammatory bowel disease 03 medical and health sciences 0302 clinical medicine 030225 pediatrics Internal medicine medicine Humans Clinical phenotype Child Crohn disease business.industry Incidence (epidemiology) Incidence Gastroenterology medicine.disease Inflammatory Bowel Diseases Ulcerative colitis Confidence interval Phenotype Pediatrics Perinatology and Child Health Population data 030211 gastroenterology & hepatology Female business New Zealand |
| Zdroj: | Journal of pediatric gastroenterology and nutrition. 66(2) |
| ISSN: | 1536-4801 |
| Popis: | BACKGROUND The incidence of paediatric inflammatory bowel disease (IBD) around the world is increasing. Canterbury, New Zealand, has one of the highest Crohn disease (CD) incidence rates published. The present study aimed to document the incidence of paediatric IBD in Canterbury between 1996 and 2015. METHODS All patients diagnosed with IBD in Canterbury, while younger than 16 years, between January 1, 1996 and December 31, 2015 were identified. Demographic and disease phenotypic details were collected and entered into a secure database. Age-specific population data for Canterbury were obtained and annual incidence rates were then calculated. RESULTS The mean annual incidence rate over the 20-year period was 7.18/100,000 (95% confidence interval 5.55-8.81) children. There was a 4-fold increase in the incidence of paediatric IBD in Canterbury between 1996 and 2015. The ratio of CD to ulcerative colitis (UC) diagnosed was 8.4:1. Disease phenotype of CD and UC, based on the Paris classification, were comparable with other studies. CONCLUSIONS The incidence of paediatric IBD in Canterbury has increased dramatically during the last 2 decades. Some of the observed incidence rates are among the highest documented anywhere in the world. The preponderance of CD over UC in the present study is the highest published. |
| Databáze: | OpenAIRE |
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