DNA methylation alterations in the genome of a toddler with cri-du-chat syndrome
| Autor: | Elena L. Grigorenko, Sergey A. Kornilov, Veronika V. Odintsova, Tatyana V. Kuznetzova, Oxana Yu. Naumova, Sergey Rychkov |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Genetics DNA methylation business.industry Cri du Chat Syndrome Chromosome Case Report cri‐du‐chat syndrome Case Reports General Medicine Disease Genome Illumina Infinium Human Methylation450 case study 03 medical and health sciences 030104 developmental biology Medicine Epigenetics Toddler business |
| Zdroj: | Clinical Case Reports |
| ISSN: | 2050-0904 |
| DOI: | 10.1002/ccr3.1274 |
| Popis: | Key Clinical Message This manuscript reports on genomewide epigenetic alterations in cri‐du‐chat syndrome related to a partial aneusomy of chromosome 5. A systematic analysis of these alterations will open up new possibilities for the prognostic evaluation of CDCS patients and the development of new therapeutic interventions for reducing the severity of the disease. |
| Databáze: | OpenAIRE |
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