Chimeric streptavidins with reduced valencies

Autor:	Kai Johnsson, Guillaume Lemercier
Předmět:	Streptavidin Strep-tag Biotin binding Tetrameric protein technology industry and agriculture Cell Biology Biochemistry Small molecule chemistry.chemical_compound Biotin chemistry Tetramer Biotinylation Molecular Biology Biotechnology
Popis:	The tight interaction between the small molecule biotin and the tetrameric protein streptavidin is widely exploited for many different applications in protein science. In this issue, researchers present the design of a monovalent streptavidin tetramer with a single biotin binding site and demonstrate its enhanced properties over wild-type streptavidin for use in cell-surface protein labeling.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbb67765dbafa26fa297c1b2f54e591b https://infoscience.epfl.ch/record/125023 Zobrazit plný text záznamu