Apgar Scores at 10 Minutes and Outcomes in Term and Late Preterm Neonates with Hypoxic-Ischemic Encephalopathy in the Cooling Era
| Autor: | Kathleen Schwabenbauer, Jay S. Greenspan, Susan C. Adeniyi-Jones, David Carola, Kiran Talekar, Dorothy McElwee, Zubair H. Aghai, Marina Ayrapetyan, Kolawole Solarin |
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| Rok vydání: | 2018 |
| Předmět: |
Neonatal intensive care unit
Time Factors Developmental Disabilities Resuscitation Encephalopathy Hypoxic Ischemic Encephalopathy Article 03 medical and health sciences 0302 clinical medicine Hypothermia Induced Intensive Care Units Neonatal Heart rate medicine Humans Retrospective Studies 030219 obstetrics & reproductive medicine medicine.diagnostic_test business.industry Infant Newborn Obstetrics and Gynecology Brain Retrospective cohort study Magnetic resonance imaging Hypothermia medicine.disease Magnetic Resonance Imaging Treatment Outcome Anesthesia Pediatrics Perinatology and Child Health Hypoxia-Ischemia Brain Apgar Score Apgar score medicine.symptom business Infant Premature |
| Zdroj: | Am J Perinatol |
| ISSN: | 1098-8785 |
| Popis: | Objective To determine the short-term outcomes (abnormal brain magnetic resonance imaging [MRI]/death) in infants born with a 10-minute Apgar score of 0 who received therapeutic hypothermia and compare them with infants with higher scores. Study Design This is a retrospective review of 293 neonates (gestational age ≥ 35 weeks) born between November 2006 and October 2015 admitted with hypoxic-ischemic encephalopathy who received therapeutic hypothermia. Results of brain MRIs were assessed by the basal ganglia/watershed scoring system. Short-term outcomes were compared between infants with Apgar scores of 0, 1 to 4, and ≥5 at 10 minutes. Results Eight of 17 infants (47%) with an Apgar of 0 at 10 minutes survived, having 4 (24%) without abnormalities on the brain MRI and 7 (41%) without severe abnormalities. There was no significant difference in the combined outcomes of “death/abnormal MRI” and “death/severe abnormalities on the MRI” between infants with Apgar scores of 0 and 1 to 4. Follow-up data were available for six of eight surviving infants, and none had moderate or severe neurodevelopmental impairment. Conclusion In the cooling era, 47% of infants with no audible heart rate at 10 minutes and who were admitted to the neonatal intensive care unit survived; 24% without abnormalities on the brain MRI and 41% without severe abnormalities. |
| Databáze: | OpenAIRE |
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