Presbylarynx: is diabetes mellitus a risk factor for vocal atrophy? A prospective case-control study
| Autor: | M Santos, A Machado, S Vaz Freitas, C Almeida e Sousa, Á Moreira da Silva |
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| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | The Journal of laryngology and otology. 136(9) |
| ISSN: | 1748-5460 0022-2151 |
| Popis: | ObjectiveTo evaluate the prevalence of diabetes mellitus type 2 in subjects with presbylarynx.MethodA case–control, prospective study was carried out on consecutive subjects who presented to the otorhinolaryngology department.ResultsThe study comprised 174 subjects (60 males and 114 females) with a mean age of 73.99 years (65–95 years). Presbylarynx was identified in 71 patients (41 per cent). Among patients with diabetes mellitus type 2, 20 patients (77 per cent) exhibited endoscopic signs of presbylarynx. A statistically significant difference was found between presbylarynx versus no presbylarynx concerning diabetes mellitus type 2 (p < 0.001). Subjects with diabetes mellitus type 2 were approximately eight times more likely to have presbylarynx compared to subjects without diabetes mellitus type 2.ConclusionIn this study, 77 per cent of patients with diabetes mellitus type 2 had endoscopic signs of presbylarynx. A multivariable analysis, which took into account co-morbidities of the elderly, identified diabetes mellitus type 2 as a possible risk factor for presbylarynx. Many physiopathological mechanisms might explain this result, as diabetes mellitus type 2 is known to affect muscular, neurological and vascular systems. |
| Databáze: | OpenAIRE |
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