Effect of fetal tissue on experimental (7,12-dimethylbenz[a]anthracene) breast cancer in rats
| Autor: | Marcelo Obando, Narisimha Rao, Maria T. Ryzlak, Rose Marie Reichle, Frederick A. Reichle, Joseph J. Noval |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
medicine.medical_specialty
business.industry 9 10-Dimethyl-1 2-benzanthracene 7 12-Dimethylbenz[a]anthracene Fetal tissue Mammary Neoplasms Experimental Long-term potentiation medicine.disease Rats chemistry.chemical_compound Fetus Endocrinology Breast cancer Liver chemistry Internal medicine Benz(a)Anthracenes Tumor regression medicine Animals Female Surgery Young adult business Homogenization (biology) |
| Zdroj: | Journal of Surgical Research. 24:563-569 |
| ISSN: | 0022-4804 |
| Popis: | Treatment with small quantities of fetal tissue from randomly bred Sprague—Dawley rats can either potentiate or depress the development of DMBA-induced breast tumors in young adult female Holtzman rats. The difference between potentiation and suppression of tumors depended upon whether the fetal tissue had been killed (by freeze—thawing and homogenization), which potentiated tumor development, or whether a viable mince of fetal tissue had been used, which greatly suppressed tumor development and caused a high rate of tumor regression. |
| Databáze: | OpenAIRE |
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