A Case of Persistent Helicobacter pylori Infection Occurring with Anti-IgE Immunosuppression

Autor: Steven F. Moss, William C. Hahn, Daniel Zandman
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: ACG Case Reports Journal
ISSN: 2326-3253
Popis: The increasingly widespread use of novel immunosuppressive drugs may lead to unexpected infectious complications. We report a case of persistent Helicobacter pylori (H. pylori) infection that failed to respond to antimicrobial therapy in a patient receiving omalizumab (Xolair™, Genentech USA Inc., San Francisco, CA and Novartis Pharmaceuticals, Basel, Switzerland), an anti-IgE monoclonal antibody approved by the FDA for treatment of severe persistent asthma. To our knowledge, this is the first case report linking an immunosuppressive regimen containing anti-IgE biologic therapy to persistent H. pylori infection.
Databáze: OpenAIRE