Tongue Nodule as Primary Manifestation of American Cutaneous Leishmaniasis in an Immunocompetent Patient

Autor: Glauco Issamu Miyahara, Ana Carolina Prado-Ribeiro, Ana Maria Pires Soubhia, Lígia Lavezo Ferreira, Stelios Fikaris, Maria Clara Bertolini Botelho, Éder Ricardo Biasoli, Daniel Galera Bernabé
Přispěvatelé: Universidade Estadual Paulista (Unesp), Universidade de São Paulo (USP)
Rok vydání: 2020
Předmět:
Zdroj: Head Neck Pathol
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
ISSN: 1936-0568
Popis: Made available in DSpace on 2021-06-25T10:47:43Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01 Leishmaniasis is a parasitic disease considered an endemic public health problem in developing countries, where it is a reportable disease. Isolated oral manifestation is rare, and its clinical manifestations are variable. In this paper we describe an unusual case of an immunocompetent patient, 57-year-old man with a painless reddish submucosal nodule located on the tongue dorsum. Microscopical analysis showed chronic inflammatory infiltrate with macrophages containing leishmania in cytoplasmic vacuoles. PCR assays confirmed the diagnosis and patient was treated with meglumine antimoniate for 30 days. Absence of the parasite was confirmed by PCR. Thirteen years after treatment, a scar fibrosis persisted on the tongue dorsum. The case reported reveals that leishmaniasis should be considered in the diagnosis of tongue nodules in immunocompetent patients. Oral Oncology Center School of Dentistry São Paulo State University (Unesp), 1193 José Bonifácio St Dental Oncology Service São Paulo State Cancer Institute (ICESP-FMUSP) University of São Paulo Medical School Department of Diagnosis and Surgery São Paulo State University (Unesp) School of Dentistry, 1193 José Bonifácio St Oral Oncology Center School of Dentistry São Paulo State University (Unesp), 1193 José Bonifácio St Department of Diagnosis and Surgery São Paulo State University (Unesp) School of Dentistry, 1193 José Bonifácio St
Databáze: OpenAIRE