Bronchial asthma on Mount Kilimanjaro is not a disadvantage
Autor: | Hannah Frost, Suzy Stokes, Andrew Davies, Mark D. Earl, I Tyrrell-Marsh, Nicholas S. Kalson, A G Whitehead |
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Rok vydání: | 2008 |
Předmět: |
Adult
Male Pulmonary and Respiratory Medicine medicine.medical_specialty Peak Expiratory Flow Rate Altitude Sickness Tanzania Bronchospasm medicine Humans Intensive care medicine Sympathetic tone Disadvantage Asthma business.industry Hypoxia (medical) Effects of high altitude on humans medicine.disease Mountaineering respiratory tract diseases Anesthesia Acute Disease Female medicine.symptom business Airway Acetazolamide medicine.drug |
Zdroj: | Thorax. 63:936-937 |
ISSN: | 0040-6376 |
DOI: | 10.1136/thx.2008.102327 |
Popis: | Every year, an increasing number of people travel to high altitude and travellers with asthma are becoming more common in remote environments.1 It is well recognised that certain situations at high altitude, such as exercising in cold air, may provoke symptoms.2 However, the mountain environment offers a reduced pollutant and allergen load, potentially causing fewer exacerbations.3 Additionally, increased sympathetic tone and adrenocortical output caused by hypoxia counteract bronchospasm. Acetazolamide, used widely by trekkers for the prophylaxis of acute mountain sickness (AMS), has an additional benefit in patients with asthma of reducing airway hyperreactivity.4 To our knowledge, this is the first prospective … |
Databáze: | OpenAIRE |
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