Individualized coronary calcium scoring at any tube voltage using a kV-independent reconstruction algorithm

Autor: Simon S. Martin, Andres F. Abadia, Riccardo Marano, U. Joseph Schoepf, Vincenzo Vingiani, Dante A. Giovagnoli, Pooyan Sahbaee, Akos Varga-Szemes, Andreas Fischer, Thomas Allmendinger, H. Todd Hudson, Fiona C. Tinnefeld
Rok vydání: 2020
Předmět:
Male
medicine.medical_specialty
Coronary calcium
Coronary Artery Disease
Coronary Angiography
030218 nuclear medicine & medical imaging
Coronary artery disease
Multidetector computed tomography
03 medical and health sciences
Radiation dosage
0302 clinical medicine
Image processing
Image processing
computer-assisted

medicine
Image acquisition
Humans
Radiology
Nuclear Medicine and imaging

Cardiac risk
Settore MED/36 - DIAGNOSTICA PER IMMAGINI E RADIOTERAPIA
business.industry
Ultrasound
Reconstruction algorithm
General Medicine
Patient specific
Middle Aged
medicine.disease
Coronary Vessels
Risk factors
030220 oncology & carcinogenesis
computer-assisted
Radiographic Image Interpretation
Computer-Assisted

Calcium
Female
Radiology
business
Tomography
X-Ray Computed

human activities
Coronary Artery Calcium Scoring
Algorithms
Zdroj: European radiology. 30(11)
ISSN: 1432-1084
Popis: We prospectively investigate the feasibility of a patient specific automated tube voltage selection (ATVS)-based coronary artery calcium scoring (CACS) protocol, using a kV-independent reconstruction algorithm, to achieve significant dose reductions while maintaining the overall cardiac risk classification.Forty-three patients (mean age, 61.8 ± 9.0 years; 40% male) underwent a clinically indicated CACS scan at 120kVp, as well as an additional CACS acquisition using an individualized tube voltage between 70 and 130kVp based on the ATVS selection (CARE-kV). Datasets of the additional CACS scans were reconstructed using a kV-independent algorithm that allows for calcium scoring without changing the weighting threshold of 130HU, regardless of the tube voltage chosen for image acquisition. Agatston scores and radiation dose derived from the different ATVS-based CACS studies were compared to the standard acquisition at 120kVp.Thirteen patients displayed a score of 0 and were correctly identified with the ATVS protocol. Agatston scores derived from the standard 120kVp (median, 33.4; IQR, 0-289.7) and the patient-tailored kV-independent protocol (median, 47.5; IQR, 0-287.5) showed no significant differences (p = 0.094). The intra-class correlation for Agatston scores derived from the two different protocols was excellent (ICC = 0.99). The mean dose-length-product was 29.8 ± 11.9 mGy × cm using the ATVS protocol and 31.7 ± 11.4 mGy × cm using the standard 120kVp protocol (p 0.001). Additionally, 95% of patients were classified into the same risk category (0, 1-10, 11-100, 101-400, or 400) using the patient-tailored protocol.ATVS-based CACS, using a kV-independent algorithm, allows for high accuracy compared to the standard 120kVp scanning, while significantly reducing radiation dose parameters.• ATVS allows for CT scanning with reduced radiation dose values. • KV-independent CACS is feasible at any tube voltage between 70 and 130 kVp. • ATVS applied to kV-independent CACS can significantly reduce the radiation dose.
Databáze: OpenAIRE