Trial of an Anti-inflammatory Agent (Indomethacin) in Low Back Pain with and without Radicular Involvement
| Autor: | M. F. Grayson, J. H. Jacobs |
|---|---|
| Rok vydání: | 1968 |
| Předmět: |
Nerve root
medicine.drug_class Indomethacin Placebo Anti-inflammatory NERVE ROOT PAIN Placebos Sciatica medicine Back pain Humans General Environmental Science Clinical Trials as Topic business.industry Headache General Engineering Papers and Originals General Medicine Low back pain Gastroenteritis Clinical trial Back Pain Anesthesia General Earth and Planetary Sciences medicine.symptom business |
| Zdroj: | BMJ. 3:158-160 |
| ISSN: | 1468-5833 0959-8138 |
| DOI: | 10.1136/bmj.3.5611.158 |
| Popis: | A short-term double-blind sequential trial of indomethacin against placebo in the treatment of low back pain, with and without nerve root pain such as sciatica, showed that indomethacin was significantly more effective than placebo in the group with nerve root pain. On the other hand, no difference was found between the treatments in the patients with uncomplicated low back pain. This difference may result from an effect of indomethacin on the inflammatory process around the nerve root which has been shown to be present when this is compressed. |
| Databáze: | OpenAIRE |
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