Corneal Endothelial Cell Density and Morphology After Acute Hydrops in Keratoconus
| Autor: | Adel H. Alsuhaibani, Ali A. Al-Rajhi, Michael D. Wagoner, Saeed Al-Motowa |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Adult
Male Keratoconus Corneal endothelium medicine.medical_specialty Adolescent genetic structures Cell Count Neovascularization Ophthalmology Humans Medicine Child Acute hydrops Microscopy Confocal business.industry Corneal Edema Endothelium Corneal medicine.disease eye diseases Ocular allergy Contact lens Endothelial cell density Acute Disease Female sense organs medicine.symptom business Corneal endothelial cell density |
| Zdroj: | Cornea. 27:535-538 |
| ISSN: | 0277-3740 |
| DOI: | 10.1097/ico.0b013e318165b92d |
| Popis: | PURPOSE To compare central corneal endothelium cell density and morphology in eyes with keratoconus and unilateral resolved hydrops with the unaffected fellow eye. METHODS Bilateral confocal microscopy was performed 3 months after resolution of acute unilateral hydrops in patients with keratoconus who presented to the King Khaled Eye Specialist Hospital between February 1, 2004, and November 31, 2005. RESULTS Twenty-six patients (19 men and 7 women) with a mean age of 22 years (range, 11-36 years) were enrolled in the study. A history of ocular allergy or rigid gas-permeable hard contact lens wear was present in 14 and 12 patients, respectively. The mean interval to resolution of hydrops was 12 weeks (range, 9-14 weeks), after which neovascularization was present in 8 eyes. The mean endothelial cell density in affected and unaffected eyes was virtually identical (2759 vs. 2788 cells/mm2, respectively; P = 0.82), although 5 (19.2%) affected eyes did have endothelial cell density that was >15% less than that of the unaffected fellow eye. Compared with unaffected eyes, there was a mean increase polymegathism in affected eyes from 33% to 35% and a mean decrease in hexagonality from 60% to 55%, but these differences were not statistically significant (P = 0.11 and 0.06, respectively). CONCLUSIONS Decreased endothelial cell density is uncommon after resolution of acute hydrops, although morphologic changes may be present in a majority of cases. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|