Forced normalization induced by ethosuximide therapy in a patient with intractable myoclonic epilepsy
| Autor: | Toshiyuki Yamamoto, Shinjiro Akaboshi, Judy R. Pipo, Sakae Narai |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Male
Psychosis medicine.medical_specialty Pediatrics medicine.medical_treatment Epilepsies Myoclonic Neurological disorder Electroencephalography Psychoses Substance-Induced Epilepsy Developmental Neuroscience medicine Humans Child Cerebral Cortex medicine.diagnostic_test General Medicine medicine.disease Surgery Ethosuximide Anticonvulsant Pediatrics Perinatology and Child Health Anticonvulsants Neurology (clinical) medicine.symptom Psychology Myoclonus Forced normalization medicine.drug |
| Zdroj: | Braindevelopment. 23(1) |
| ISSN: | 0387-7604 |
| Popis: | Forced normalization (FN) is a well known phenomenon of acute psychosis accompanying seizure control. An 11-year-old boy with intractable myoclonic epilepsy and severe psychomotor delay experienced FN during medication of ethosuximide. Although his myoclonic seizures were completely controlled, behavioral changes, more of the manic type, became evident. EEG during this phenomenon showed almost normal findings. Generally, withdrawal of anti-epileptic drugs in patients with FN is still controversial and much debated. We could conclude that the physician should judge comprehensively the treatment considering the more favorable situation for the patient and the family. |
| Databáze: | OpenAIRE |
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