In vitro autodegradation of ribosomal RNA formation of specific fragments with endonucleolytic cleavages

Autor: Tadashi Inoue, Hikoyuki Yamaguchi, Yasukiyo Umemura
Rok vydání: 1975
Předmět:
Zdroj: Biochemical and Biophysical Research Communications. 62:176-183
ISSN: 0006-291X
DOI: 10.1016/s0006-291x(75)80120-3
Popis: Summary When incubated in vitro with EDTA, ribosomal RNA in fetal rat liver polysomes was degraded to produce fragments some of which have molecular weights similar to those of in vivo degradation intermediates of 28S ribosomal RNA. The degradation occurred endonucleolytically and was inhibited by SDS and liver “cell sap”.
Databáze: OpenAIRE