Clinical Immunology Review Series: An approach to the patient with recurrent infections in childhood
| Autor: | Andrew R. Gennery, Mary Slatter |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Adolescent
medicine.drug_class End organ damage Immunology Antibiotics Opportunistic Infections Chronic granulomatous disease Quality of life Recurrence Immunity Immunopathology medicine Humans Immunology and Allergy Age of Onset Child Severe combined immunodeficiency business.industry Patient Selection Immunologic Deficiency Syndromes Infant Newborn Infant medicine.disease Clinical Immunology Review Series Child Preschool Primary immunodeficiency business |
| Zdroj: | Clinical and Experimental Immunology. 152:389-396 |
| ISSN: | 1365-2249 0009-9104 |
| DOI: | 10.1111/j.1365-2249.2008.03641.x |
| Popis: | Summary Recurrent or persistent infection is the major manifestation of primary immunodeficiency, which also results in atypical infection with opportunistic organisms. Young children are also vulnerable to infection and recurrent infection is common. While most children with recurrent infection have a normal immunity, it is important to recognize the child with an underlying primary immunodeficiency and investigate and treat appropriately and yet not over investigate normal children. Prompt, accurate diagnosis directs the most appropriate treatment, and early and judicious use of prophylactic antibiotics and replacement immunoglobulin can prevent significant end organ damage and improve long-term outlook and quality of life. This paper describes important presenting features of primary immunodeficiency and indicates when further investigation is warranted. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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