Assessment of clinicopathological features, evaluation of treatment, and prognosis of clear cell and serous papillary endometrial carcinoma
| Autor: | Mehmet Sipahi, Cenk Nayki, Pasa Ulug, Mehmet Kulhan, Yusuf Yildirim, Umit Nayki, Gozde Kulhan |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
0301 basic medicine Oncology medicine.medical_specialty Lymphovascular invasion Gravidity Metastasis 03 medical and health sciences 0302 clinical medicine Internal medicine Antineoplastic Combined Chemotherapy Protocols Carcinoma medicine Adjuvant therapy Humans Neoplasm Invasiveness Stage (cooking) Lymph node Aged business.industry Obstetrics and Gynecology Middle Aged medicine.disease Survival Analysis Carcinoma Papillary Endometrial Neoplasms Parity Serous fluid 030104 developmental biology medicine.anatomical_structure CA-125 Antigen Lymphatic Metastasis 030220 oncology & carcinogenesis Clear cell carcinoma Female Radiotherapy Adjuvant Neoplasm Recurrence Local business Adenocarcinoma Clear Cell |
| Zdroj: | Ginekologia Polska. 87:570-574 |
| ISSN: | 0017-0011 |
| Popis: | Objectives: We aimed to evaluate and compare the clinical and pathological features, diagnosis, treatment, and prognosis of uterine papillary serous carcinoma (UPSC) and clear-cell carcinoma (CC). Material and methods: Thirty-four patients who were operated on for UPSC and CC carcinoma at the Izmir Tepecik Research and Teaching Hospital, between January 1983 and December 2014, were included. Patients were evaluated for the following factors: age, gravidity, parity, preoperative CA-125, tumor size, myometrial and lymphovascular invasion, lymph node tumor metastasis, presence of atypical cells in peritoneal cytology, pathology results, operation types, whether or not they received postoperative adjuvant therapy, prognosis, and death rate. Results: The stage of the disease was the main factor affecting disease-free and the overall survival. Cisplatin-based chemotherapy was partially effective in patients with postoperative recurrence, while postoperative adjuvant radiotherapy proved to be more effective in preventing relapse. Conclusion: The studied parameters generally were concordant with the literature but, due to the relatively small sample size, more comprehensive and multicenter studies are needed to generate valid results. |
| Databáze: | OpenAIRE |
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