Asymmetry of lower esophageal sphincter pressure: is it related to the muscle thickness or its shape?
| Autor: | Ravinder K. Mittal, V. K. Parashar, Jianhua Liu |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Adult
Male Manometry Physiology media_common.quotation_subject Asymmetry Lower esophageal sphincter pressure Physiology (medical) Circular muscle Pressure otorhinolaryngologic diseases medicine Humans Esophagus Ultrasonography media_common Hepatology business.industry Chemistry Stomach Gastroenterology Muscle Smooth Longitudinal muscle Anatomy medicine.anatomical_structure Esophageal sphincter Female Dynamic pressure Esophagogastric Junction business |
| Zdroj: | American Journal of Physiology-Gastrointestinal and Liver Physiology. 272:G1509-G1517 |
| ISSN: | 1522-1547 0193-1857 |
| Popis: | Lower esophageal sphincter (LES) pressure shows axial and circumferential asymmetry, the reasons for which are not clear. Our aim was to determine whether the muscle thickness and shape of the LES were the reasons for the axial and circumferential asymmetry in the LES pressure. High-frequency, catheter-based intraluminal ultrasonography was performed to obtain images of the human LES and esophagus. Station pull-through manometry was performed to record the axial and circumferential asymmetry of LES pressure. Circular and longitudinal muscle were thicker in the LES compared with in the esophagus. There was a close correlation between the axial asymmetry in LES pressure and circular muscle thickness. The thickness of LES muscle increased and decreased with an increase and decrease in the LES pressure, respectively. The circumferential asymmetry in resting LES pressure was related to the noncircular shape of the LES. A swallow-induced LES relaxation was followed by its contraction. During the contraction phase, the LES and esophagus showed relative symmetry in pressure and shape. We conclude that the axial asymmetry of LES pressure is explained by its muscle thickness. On the other hand, circumferential asymmetry is related to the noncircular shape of the LES. |
| Databáze: | OpenAIRE |
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