Depiction of residual emboli following pulmonary embolism with thrombotic scintigraphy
| Autor: | Kenji Hiromoto, Keiko Takahashi, Mamoru Ohnishi, Hitoshi Naruse, Mitsumasa Ohyanagi, Atsunori Ueda |
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| Rok vydání: | 2005 |
| Předmět: |
Adult
Blood Platelets Male medicine.medical_specialty Venography Scintigraphy Sensitivity and Specificity Recurrence Internal medicine Organometallic Compounds Humans Medicine Radiology Nuclear Medicine and imaging Treatment Failure cardiovascular diseases Stage (cooking) Aged Aged 80 and over medicine.diagnostic_test business.industry Warfarin Reproducibility of Results General Medicine Heparin Middle Aged Pelvic cavity Oxyquinoline Prognosis medicine.disease Pulmonary embolism Treatment Outcome medicine.anatomical_structure Positron-Emission Tomography Circulatory system Cardiology Female Radiology Radiopharmaceuticals Pulmonary Embolism business medicine.drug |
| Zdroj: | Annals of Nuclear Medicine. 19:641-645 |
| ISSN: | 1864-6433 0914-7187 |
| DOI: | 10.1007/bf02985111 |
| Popis: | In the treatment of pulmonary embolism (PE), the presence of residual emboli is known to seriously affect the recurrence and prognosis. We attempted to depict the residual emboli in the subacute stage of PE using indium-111-oxine labeled platelet scintigraphy (In-plt). In-plt was performed on 22 patients with PE who showed an improvement according to lung perfusion scintigraphy. Their accumulation was assessed along with the blood coagulation ability measured on the same day. In addition, radioisotope venography (RI-veno) was performed simultaneously with In-plt to measure the circulatory findings in the lower limb for comparison. All patients received systemic heparin during the acute stage and received warfarin at the time of testing. Accumulation of In-plt was observed in 7 patients (32%), and positive signals were found in the lower limbs or pelvic cavity in all cases. Two patients were suspected of having poor lower limb circulation from their Rl-veno findings, and these findings were largely consistent with the areas of In-plt accumulation. Some emboli persist after extensive anti-coagulation therapy. The use of In-plt is effective in determining the therapeutic measures and assessing the prognosis as this method allows us to clearly depict the existence of such emboli. |
| Databáze: | OpenAIRE |
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