Caesarean delivery is associated with increased blood pressure in young adult offspring
Autor: | Amaraporn Rerkasem, Sarah E. Maessen, Sakda Pruenglampoo, Ampica Mangklabruks, Patumrat Sripan, Kittipan Rerkasem, Antika Wongthanee, José G. B. Derraik |
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Rok vydání: | 2021 |
Předmět: |
Male
medicine.medical_specialty Mean arterial pressure Offspring Science medicine.medical_treatment Diastole Blood Pressure 030204 cardiovascular system & hematology Carotid Intima-Media Thickness Body Mass Index Cohort Studies Young Adult 03 medical and health sciences 0302 clinical medicine Risk Factors Humans Medicine Arterial Pressure Caesarean section Obesity Prospective Studies 030212 general & internal medicine Young adult Multidisciplinary Anthropometry Cesarean Section business.industry Obstetrics Public Health Global Health Social Medicine and Epidemiology Thailand Folkhälsovetenskap global hälsa socialmedicin och epidemiologi Blood pressure Cardiovascular Diseases Heart Disease Risk Factors Relative risk Hypertension Adult Children Female business |
Zdroj: | Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021) |
ISSN: | 2045-2322 |
Popis: | We examined the associations between caesarean section (CS) delivery and cardiovascular risk factors in young adults in Thailand. Participants were 632 offspring from a birth cohort in Chiang Mai (Northern Thailand), born in 1989–1990 and assessed in 2010 at a mean age of 20.6 years, including 57 individuals (9.0%) born by CS and 575 born vaginally. Clinical assessments included anthropometry, blood pressure (BP), carotid intima-media thickness, and fasting blood glucose, insulin, and lipid profile. Young adults born by CS had systolic BP (SBP) 6.2 mmHg higher (p p = 0.029), and mean arterial pressure (MAP) 4.1 mmHg higher (p = 0.003) than those born vaginally. After covariate adjustments, SBP and MAP remained 4.1 mmHg (p = 0.006) and 2.9 mmHg (p = 0.021) higher, respectively, in the CS group. The prevalence of abnormal SBP (i.e., pre-hypertension or hypertension) in the CS group was 2.5 times that of those born vaginally (25.0% vs 10.3%; p = 0.003), with an adjusted relative risk of abnormal SBP 1.9 times higher (95% CI 1.15, 2.98; p = 0.011). There were no differences in anthropometry (including obesity risk) or other metabolic parameters. In this birth cohort in Thailand, CS delivery was associated with increased blood pressure in young adulthood. |
Databáze: | OpenAIRE |
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