7-{4-[(1,3-Benzodioxol-5-yl)meth-yl]piperazin-1-yl}-1-cyclo-propyl-6-fluoro-4-oxo-1,4-dihydro-quinoline-3-carb-oxy-lic acid

Autor:	Guang-Zhi Shan, Mingliang Liu, Shuo Wang, Huiyuan Guo
Rok vydání:	2012
Předmět:	Hydrogen bond Quinoline General Chemistry Meth Condensed Matter Physics Ring (chemistry) Bioinformatics Medicinal chemistry Carbonyl group Organic Papers lcsh:Chemistry chemistry.chemical_compound lcsh:QD1-999 chemistry General Materials Science
Zdroj:	Acta Crystallographica Section E: Structure Reports Acta Crystallographica Section E, Vol 68, Iss 7, Pp o2264-o2264 (2012)
ISSN:	1600-5368
Popis:	In the title structure, C25H24FN3O5, a strong intramolecular O—H...O hydrogen bond is present between the carboxy group at the 3-position and the carbonyl group at the 4-position. In the crystal, molecules are held together by weak C—H...O, C—H...F and π–π [centroid–centroid distance 3.6080 (8) Å] interactions. The 1,4-dihydroquinoline ring and cyclopropyl group are not in the same plane, making an interplanar angle of 57.52 (8)°.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db6e861174247f31c877482746cf1eea https://pubmed.ncbi.nlm.nih.gov/22798912 Zobrazit plný text záznamu