Prevalence of allergic symptoms among children with diabetes mellitus type 1 of different socioeconomic status
| Autor: | Eleni Tsoka, Catherine Dacou-Voutetakis, Maria Brisimitzi, Kostas Kakleas, Maria Mavrikiou, Kyriaki Karavanaki, Eleni Pippidou, Ilias Konstantopoulos, Vassilis Petrou, Manolis Manoussakis, Christina Karayianni |
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| Rok vydání: | 2008 |
| Předmět: |
Male
musculoskeletal diseases congenital hereditary and neonatal diseases and abnormalities Pediatrics medicine.medical_specialty Allergy Endocrinology Diabetes and Metabolism Infections Social class Surveys and Questionnaires Diabetes mellitus Hypersensitivity Prevalence Internal Medicine Humans Medicine Child Socioeconomic status Asthma Univariate analysis Type 1 diabetes business.industry Vaccination medicine.disease Breast Feeding Diabetes Mellitus Type 1 Social Class Pediatrics Perinatology and Child Health Female business |
| Zdroj: | Pediatric Diabetes. 9:407-416 |
| ISSN: | 1399-5448 1399-543X |
| DOI: | 10.1111/j.1399-5448.2008.00444.x |
| Popis: | The aim of the study was to assess the possible associations between allergies and type 1 diabetes mellitus (DM1), stratified by social class. We studied 127 children with DM1 with a median age of 10.8 yr and 150 controls of comparable age and sex distribution. The parents completed questionnaires on their education and occupation and on their children’s history of allergic symptoms, breast-feeding, viral infections, and measles–mumps–rubella (MMR) vaccination. Lower family’s social class was more frequently encountered among the DM1 families than in the controls (OR = 0.56, 95% CI: 0.35–0.92). The occurrence of any allergic symptoms among children with DM1 (35.45%) was not significantly different from the controls (38.78%), neither in the total group (OR = 0.87, 95% CI: 0.52–1.45) nor in the stratified analysis by social class. Similar findings were observed regarding the different types of allergic symptoms. In the univariate analysis, breast-feeding, the experience of viral infections, and MMR vaccination were found to be protective of DM1 presentation in both upper and lower social classes. In the multiple logistic regression analysis, the experience of more than 2 infections/yr (OR = 0.12, 95% CI: 0.04–0.34), the origin from middle and upper social classes (OR = 0.42, 95% CI: 0.22–0.80) and breast-feeding (OR = 0.58, 95% CI: 0.31–1.07) were protective of DM1 occurrence. In children with DM1, the presence of allergic symptoms was not associated with the development of DM1. Among the environmental factors, the origin from middle or upper social classes, breast-feeding, the experience of viral infections, and MMR vaccination were found to have a protective effect on DM1 presentation. |
| Databáze: | OpenAIRE |
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